Not all saponins have a greater antiprotozoal activity than their related sapogenins
نویسندگان
چکیده
منابع مشابه
Saponins and Sapogenins
The seeds of Luffa aegyptica Mill, locally known as "ghia torai" (family Cucurbitaceae), have earlier been studied for the saponin and sapogenin contents and found to contain a mixture of colourless saponins which on hydrolysis yields two acid and a neutral sapogenin. The acetates of the two acid genins melted at 266-268" and 176-181" while the neutral genin acetate melted at 262-264O.l The aci...
متن کاملSaponins and Sapogenins from Brachiaria decumbens Stapf
Quatro saponinas esteroidais e três sapogeninas foram identificadas das partes aéreas de Brachiaria decumbens. As estruturas desses compostos foram estabelecidas através de métodos químicos e espectroscópicos (RMN de H e C, HMBC, HMQC) como 3 -metóxi-lanost-9(11)-eno (1), diosgenina (2a), iamogenina (2b), 3-O-D-glicopiranosil-24(S)-etil-22E-deidrocolesterol (3a), 3O-D-glicopiranosil-24(R)-etil-...
متن کاملImproving the antiprotozoal effect of saponins in the rumen by combination with glycosidase inhibiting iminosugars or by modification of their chemical structure
The antiprotozoal effect of saponins is transitory, as when saponins are deglycosylated to sapogenins by rumen microorganisms they become inactive. We hypothesised that the combination of saponins with glycosidase-inhibiting iminosugars might potentially increase the effectiveness of saponins over time by preventing their deglycosylation in the rumen. Alternatively, modifying the structure of t...
متن کاملAntiprotozoal Effect of Saponins in the Rumen Can Be Enhanced by Chemical Modifications in Their Structure
The antiprotozoal effect of saponins is transitory, as when saponins are deglycosylated to the sapogenin by rumen microorganisms they become inactive. We postulated that the substitution of the sugar moiety of the saponin with small polar residues would produce sapogen-like analogs which might be resistant to degradation in the rumen as they would not be enzymatically cleaved, allowing the anti...
متن کاملBone mineral density loss in postmenopausal onset rheumatoid arthritis is not greater than premenopausal onset disease
Background: Postmenopausal onset rheumatoid arthritis (post-RA) is expected to have greater bone mineral density (BMD) loss than premenopauasal onset (pre-RA) due to estrogen deficiency and aging. This study aimed to compare the BMD status of the two RA groups with age-matched non-RA controls. Methods: The patients with RA on follow-up examination were stratified according to age of onset. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 2019
ISSN: 1574-6968
DOI: 10.1093/femsle/fnz144